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human probdnf duoset elisa  (R&D Systems)


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    R&D Systems human probdnf duoset elisa
    Human Probdnf Duoset Elisa, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/probdnf+duoset+human/Human+Pro-BDNF+DuoSet+ELISA/pm41013853-55-26-31
    Average 93 stars, based on 57 article reviews
    human probdnf duoset elisa - by Bioz Stars, 2026-09
    93/100 stars

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    Characteristics of subjects with autism.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Characteristics of subjects with autism.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques:

    Characteristics of control subjects.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Characteristics of control subjects.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques: Control

    Serum protein levels measured by ELISA. ( a ) IGF-1, ( b ) total BDNF, ( c ) proBDNF and ( d ) the ratio of proBDNF/total BDNF immunoreactive protein levels in serum of controls (n = 29, or n = 28 where indicated) and subjects with autism (n = 22). 2-tailed Mann–Whitney test, IGF-1 *p = 0.037, total BDNF p = 0.350, ns not significant; proBDNF **p = 0.005, controls n = 28; proBDNF/total BDNF *p = 0.024, controls n = 28. Data are shown as mean ± SEM.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Serum protein levels measured by ELISA. ( a ) IGF-1, ( b ) total BDNF, ( c ) proBDNF and ( d ) the ratio of proBDNF/total BDNF immunoreactive protein levels in serum of controls (n = 29, or n = 28 where indicated) and subjects with autism (n = 22). 2-tailed Mann–Whitney test, IGF-1 *p = 0.037, total BDNF p = 0.350, ns not significant; proBDNF **p = 0.005, controls n = 28; proBDNF/total BDNF *p = 0.024, controls n = 28. Data are shown as mean ± SEM.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques: Enzyme-linked Immunosorbent Assay, MANN-WHITNEY

    Serum BDNF and IGF-1 protein levels in unmedicated and medicated subjects. BDNF and IGF-1 immunoreactive protein levels in serum of unmedicated (n = 8) and medicated (n = 14) subjects with autism and in non-autistic controls (n = 29 or n = 28 where indicated). Kruskal–Wallis test, ( a ) total BDNF, p = 0.073; ( b ) proBDNF **p = 0.004 followed by Dunn’s test unmedicated vs. medicated p = 0.187, unmedicated vs. controls p > 0.999, medicated vs. controls **p = 0.003, controls n = 28; ( c ) proBDNF/total BDNF p = 0.070, controls n = 28; ( d ) IGF-1 p = 0.108. Data are shown as mean ± SEM.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Serum BDNF and IGF-1 protein levels in unmedicated and medicated subjects. BDNF and IGF-1 immunoreactive protein levels in serum of unmedicated (n = 8) and medicated (n = 14) subjects with autism and in non-autistic controls (n = 29 or n = 28 where indicated). Kruskal–Wallis test, ( a ) total BDNF, p = 0.073; ( b ) proBDNF **p = 0.004 followed by Dunn’s test unmedicated vs. medicated p = 0.187, unmedicated vs. controls p > 0.999, medicated vs. controls **p = 0.003, controls n = 28; ( c ) proBDNF/total BDNF p = 0.070, controls n = 28; ( d ) IGF-1 p = 0.108. Data are shown as mean ± SEM.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques:

    Correlations between serum IGF-1 and BDNF immunoreactivity and age. Spearman’s correlations: ( a ) IGF-1 correlation of all samples with age, r s = 0.345, p = 0.013, n = 51. ( b ) IGF-1 correlation of each group separately with age (control group r s = 0.207, p = 0.282, n = 29; autism group r s = 0.429, p = 0.046, n = 22). ( c ) Total BDNF correlation of all samples with age, r s = − 0.233, p = 0.101, n = 51. ( d ) Total BDNF and proBDNF correlations with age in the control group (total BDNF r s = − 0.436, p = 0.018, n = 29; proBDNF r s = 0.516, p = 0.005, n = 28). ( e ) Total BDNF and proBDNF correlations with age in the autism group (total BDNF r s = − 0.010, p = 0.966, n = 22; proBDNF r s = − 0.205, p = 0.359, n = 22. ( f ) Correlation of proBDNF/total BDNF in each group separately with age (control group r s = 0.469, p = 0.012, n = 28; autism group r s = − 0.075, p = 0.739, n = 22). Open triangles, controls; filled circles, autism; open diamonds, total BDNF; closed diamonds, proBDNF.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Correlations between serum IGF-1 and BDNF immunoreactivity and age. Spearman’s correlations: ( a ) IGF-1 correlation of all samples with age, r s = 0.345, p = 0.013, n = 51. ( b ) IGF-1 correlation of each group separately with age (control group r s = 0.207, p = 0.282, n = 29; autism group r s = 0.429, p = 0.046, n = 22). ( c ) Total BDNF correlation of all samples with age, r s = − 0.233, p = 0.101, n = 51. ( d ) Total BDNF and proBDNF correlations with age in the control group (total BDNF r s = − 0.436, p = 0.018, n = 29; proBDNF r s = 0.516, p = 0.005, n = 28). ( e ) Total BDNF and proBDNF correlations with age in the autism group (total BDNF r s = − 0.010, p = 0.966, n = 22; proBDNF r s = − 0.205, p = 0.359, n = 22. ( f ) Correlation of proBDNF/total BDNF in each group separately with age (control group r s = 0.469, p = 0.012, n = 28; autism group r s = − 0.075, p = 0.739, n = 22). Open triangles, controls; filled circles, autism; open diamonds, total BDNF; closed diamonds, proBDNF.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques: Control

    Correlations between Childhood Autism Rating Scale (CARS) scores and IGF-1 and proBDNF/BDNF. ( a ) IGF-1 immunoreactivity, Spearman’s correlation r s = 0.486, p = 0.022 and ( b ) ratio proBDNF/BDNF, Spearman’s correlation r s = − 0.407, p = 0.060. n = 22.

    Journal: Scientific Reports

    Article Title: BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

    doi: 10.1038/s41598-022-17503-6

    Figure Lengend Snippet: Correlations between Childhood Autism Rating Scale (CARS) scores and IGF-1 and proBDNF/BDNF. ( a ) IGF-1 immunoreactivity, Spearman’s correlation r s = 0.486, p = 0.022 and ( b ) ratio proBDNF/BDNF, Spearman’s correlation r s = − 0.407, p = 0.060. n = 22.

    Article Snippet: BDNF, proBDNF and IGF-1 ELISA: Serum BDNF, proBDNF and IGF-1 were measured using the Human BDNF DuoSet ELISA kit DY248, Human proBDNF DuoSet ELISA kit DY3175 and Human IGF-1 Quantikine ELISA kit DG100 (R&D Systems, Minneapolis, MN, US).

    Techniques: